==============A letter from Dr John Lee==================

27 December 1997

To: AIM International, Inc. and all distributors of xxxxxxxxxxxxxxxxxxxx

From: John R. Lee, MD

In my book, What Your Doctor May Not Tell You About Menopause, the dosage recommendations (e.g. 1/4 tsp, etc.) refers to creams containing about 450-500 mg/ounce As you know, xxxxxxx xxxxxxxx contains 750 mg/ounce, or approximately 50% more progesterone. Thus, the book's dosage recommendations are not correct when xxxxxxx xxxxxxx is used.

Because of this difference in progesterone concentration, xxxxxxxxxxxxxxx is not listed on page 271 of the latest printing of my book which contains a list of creams containing progesterone concentrations of 400-500 mg per ounce.

However, as I have repeatedly stated, xxxxxxxxxxxxxxx is a good cream butthe amount of cream to be used to obtain the progesterone dosages (15-20 mg/day) I recommend for the usual female with progesterone deficiency should be reduced proportionately.

For example, if a woman wished to use 20 mg of progesterone for 15 days per month, her total monthly dose would be 300 mg. If this were obtained from a cream containing 900 mg of progesterone per 2-ounce container, she would need just 1/3 of a container each month. If xxxxxxxxxxxxxxxx is used, this same monthly progesterone dose would require only 1/5 of a jar. (20 mg is 1/8th teaspoon of xxxxxxxxxxxxxxxxxxx)

If a postmenopausal woman wished to use 15 mg of progesterone per day for 25 days each month, her monthly dose would be 15 x 25 = 375 mg. This is exactly 1/4 of a jar of xxxxxxxxxxxxxxxxx. Thus, each jar would last for 4 months.
When used proportionately in this manner, xxxxxxxxxxxxxxxxxxxxx cream will properly supply the recommended amount of progesterone as I describe in my book.

John R. Lee, MD

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